Chemosensitization Effect of Seabuckthorn Pulp Oil in NSCLC Cells
Lung cancer is the leading cause of cancer-related death worldwide. In contrast, the 5-year relative survival rate for all stages of lung cancer is approximately 21%, with the major histological subtype being non-small-cell lung cancer (NSCLC). The gold standard for NSCLC treatment remains the cisplatin-based chemotherapy regimen. However, prolonged use of chemotherapeutic agents might increase toxicities [...]
Anthelmintic Activity of Sea Buckthorn Fruit Juice against Gastrointestinal Nematodes of Small Rumin
Hippophae rhamnoides, also known as sea buckthorn, is a good plant, as it is a rich source of valuable bioactive components. Several studies have investigated its broad biological properties, and its uses range from the medical and cosmetic fields to the industrial food sector. The whole plant is rich in bioactive antioxidant and immunomodulating compounds, and hippophae rhamnoides berries, leaves, [...]
Seabuckthorn Powder Protects against High-Fat Diet-Induced Obesity, Lipid Metabolism Disorders
Obesity is the accumulation of excess fatty tissue, accompanying the increase of body weight and fat deposition in the liver, causing corresponding metabolism dysfunction. Evidence showed that consuming foods rich in bioactive compounds, such as fruits and vegetables, could benefit anti-obesity and obesity-association metabolism diseases. Our study showed that daily supplementation with seabuckthorn freeze-dried powder at [...]
Anti‐Hyperglycemic Effects of Sea Buckthorn Oil and Extract
We comprehensively analyze the effect of sea buckthorn (Hippophaes rhamnoides) on glucose homeostasis on central regulatory steps of postprandial glucose metabolism. Various biological models were utilized as complementary systems, including human cell lines, non‐vertebrate organisms, and the chick embryo model. Sea buckthorn is a rich source of biologically active compounds that benefit human health. In particular, [...]
Sea Buckthorn Oil Enhances Proliferation, Adipocytes Differentiation and Insulin Sensitivity
Effect of sea buckthorn oil on 3T3-L1 pre-adipocytes proliferation Cytotoxicity is one key indicator in evaluating the effects of a particular chemical compound on a given cell line. In our study, the Lactate dehydrogenase (LDH) assay was employed to determine the cytotoxicity of sea buckthorn oil on 3T3-L1 preadipocytes. The addition of sea buckthorn oil at [...]
The Effect of Sea Buckthorn Seed Oil in Lipid Metabolism of Human Skin
As the major components of the outer skin layer are lipids, we can infer that using lipid derivatives will enhance skin conditions. Therefore, plant oils can be used as a source of compounds that may protect skin cells due to their multidirectional activities, including anti-inflammatory, antibacterial, and antioxidants, as well as the source of fatty acids. [...]
Effect of Sea Buckthorn on Plasma Glucose
Sea buckthorn has hypoglycemic potential; we conducted a test to determine its effects on glucose in people with impaired glucose regulation (IGR). A total of 38 subjects with IGR completed the intervention of consuming sea buckthorn fruit puree (90 mL/day, five weeks), washing out (four weeks), and then consuming placebo (90 mL/day, five weeks). Our results [...]
Skin Penetration of Natural Oils
We carried out a study to evaluate the skin penetration of natural oils and their potential application as skin penetration enhancers for dihydroquercetin (DHQ) delivery. We found that applying olive oil, avocado oil, soybean oil, sea buckthorn oil, coconut oil, and soybean oils increases the content of fatty acids (FAs) in the ex vivo skin layers. [...]
Effect of Sea Buckthorn on Plasma Glucose Regulation
Sea buckthorn has hypoglycemic potential. We carried out a randomized, double-blinded, two-way crossover study to discover its effects on glucose in people with impaired glucose regulation (IGR). According to the final data, the detection rate of IGR was 32.4% (45/139). Considering that IGR contributes to a high risk of type 2 diabetes and other metabolic diseases, [...]