Hypoglycaemic activity of Ganoderma triterpenoids A series of in vitro studies have showed that Ganoderma lucidum (fruiting bodies) extract, including reishi spore oil and reishi spore powder, has a strong inhibitory effect on human aldose reductase activity. Ganoderic acid Df, a lanostane-type triterpenoid, exhibited potent aldose reductase inhibitory activity with an IC50 value of 22.8µM. It was subsequently demonstrated that ganoderol B, which was isolated [...]