Ganodermanondiol, a New Melanogenesis Inhibitor from Ganoderma lucidum
Chemical Structure and Cytotoxicity of Ganodermanondiol Isolated from Ganoderma lucidum on B16F10 Melanoma Cells Previous studies of G. lucidum have established that it contains more than 300 biologically active compounds such as triterpenoids, polysaccharides, and steroids. Initially, the ethanol (EtOH) extract of dried G. lucidum was suspended in water and partitioned successively with ethyl acetate (EtOAc). Using bioassay-guided fractionation, the [...]