There is some evidence to suggest that organic germanium may increase energy levels. A 2011 study published in the journal "Evidence-Based Complementary and Alternative Medicine" found that oral supplementation with organic germanium improved energy levels in people with chronic fatigue syndrome. The study found that germanium helped to increase the production of ATP, the body's primary [...]
There is some evidence to suggest that organic germanium may improve mental function. A 2012 study published in the journal "Nutritional Neuroscience" found that oral supplementation with organic germanium enhanced cognitive function in people with Alzheimer's disease. The study found that germanium helped increase blood flow to the brain, promoting new neuron growth. Additionally, germanium helps [...]
Lung cancer is the leading cause of cancer-related death worldwide. In contrast, the 5-year relative survival rate for all stages of lung cancer is approximately 21%, with the major histological subtype being non-small-cell lung cancer (NSCLC). The gold standard for NSCLC treatment remains the cisplatin-based chemotherapy regimen. However, prolonged use of chemotherapeutic agents might increase toxicities [...]
Myelodysplastic syndromes (MDS) are a heterogeneous group of clonal bone marrow stem cell disorders characterized by ineffective erythropoiesis with dysplastic bone marrow leading to peripheral blood cytopenias a variable propensity for progression to acute myelogenous leukemia (AML). Neutropenia occurs in 50 % of newly diagnosed patients, more frequently in those with higher-risk (70–80 %) than lower-risk [...]
Parkinson's disease (PD) is a neurodegenerative disease with an estimated 2–3% prevalence in the population above 65 years of age. The prevalence increases with age, from 1% at age 45–55 to 4% (men) and 2% (women) at age 85. Typical examples are the motor symptoms related to (nonreversible) loss of dopaminergic cells in the substantia nigra. [...]
Alzheimer's disease (AD) is characterized by the deposition of amyloid-β (Aβ) plaques, neuronal loss, and neurofibrillary tangles. In addition, neuroinflammatory processes are thought to contribute to AD pathophysiology. Maitake (Grifola frondosa), an edible/medicinal mushroom, exhibits high nutritional value and contains many health-beneficial, bioactive compounds. It has been reported that proteo-β-glucan, a polysaccharide derived from Maitake (PGM), [...]
Lion’s Mane Lion’s mane (Hericium erinaceus), an edible and medicinal mushroom species, is widespread across East Asia. Its medicinal properties have been known for several ages, as evidenced by its use in traditional Asian folk medicine. The bioactive compounds identified in Lion’s mane include indole, fenol, steroid, and lactone compounds, terpenoids (erinacines, hericerins, and hericenones.), alkaloids (hericirine), polysaccharides, [...]
Coriolus Versicolor (CV), also known as Turkey Tail, is a kind of folk medicine and edible fungus growing on tree trunks. The main components of CV are proteins, fats, polysaccharides, polysaccharide peptides, glucans, amino acids, and a variety of inorganic salts. Coriolus Versicolor polysaccharide (CVP) is one of the important bioactive substances in CV. It has [...]
As part of traditional Chinese medication regimens, cordyceps extract has previously been shown to ameliorate various diseases, including metabolic anomalies. However, it needs to be clarified what the bioactive ingredient in cordyceps extracts is and the molecular mechanisms through which these extracts elicit beneficial effects. Here we demonstrate that myriocin, a pharmacological inhibitor of ceramide biosynthesis in [...]