We carried out a study to evaluate the skin penetration of natural oils and their potential application as skin penetration enhancers for dihydroquercetin (DHQ) delivery. We found that applying olive oil, avocado oil, soybean oil, sea buckthorn oil, coconut oil, and soybean oils increases the content of fatty acids (FAs) in the ex vivo skin layers. [...]
Sea buckthorn has hypoglycemic potential. We carried out a randomized, double-blinded, two-way crossover study to discover its effects on glucose in people with impaired glucose regulation (IGR). According to the final data, the detection rate of IGR was 32.4% (45/139). Considering that IGR contributes to a high risk of type 2 diabetes and other metabolic diseases, [...]
Botanical oils contain complex mixtures of saturated and unsaturated fatty acids, typically esterified in triglycerides. These fatty acids act as powerful lipophilic solvents to selectively extract and accumulate non-polar secondary metabolites produced by the source plants. Although data is limited, the most efficient solvent-like molecules in the fixed (oleic and linoleic acids) and essential (limonene) botanical [...]
Unsaturated fatty acids present themselves as colorless liquids under normal conditions and are classified into monounsaturated (MUFA) and polyunsaturated (PUFA) fatty acids. They are further distinguished accordingly to the number and location of the double cis bonds about the carboxyl terminus as omega- (n-, delta-) 12, 11, 9, 7, 6, 5, and 3 fats. Two fatty [...]
Botanical oils are complex mixtures of triacylglycerols (fatty acid esters of glycerol) with some minor components such as tocopherols, phytosterols, and polyphenols that are either cold-pressed (virgin oils), solvent extracted, or super critical extracted. Saturated fatty acids present in botanical oils do not contain double bonds. Caprylic Acid 8:0 and Capric Acid 10:0 These saturated fatty acids are [...]
Alpha-linolenic acid or α-Linolenic acid (ALA) (18:3n-3) is an 18-carbon fatty acid with three double bonds at carbons 9, 12, and 15. It is an essential n-3 fatty acid which is a required nutrient for humans and can be obtained through diets including both plant and animal sources. ALA can be converted by elongases and desaturases [...]
Nowadays, due to their functional and health‐promoting properties, consumers are increasingly choosing non-traditional oils, including sea buckthorn oil, flaxseed oil, hempseed oil, and camellia seed oil. Sea buckthorn pulp oil, also called seabuckthorn fruit oil, has a high content of palmitoleic acid; however, sea buckthorn seed oil and pulp oil have a different fatty acid (FA) profile. Sea buckthorn seeds contain 12.5% oil, [...]
Our study shows that Ganoderma lucidum/reishi/lingzhi shows antitumor properties on osteosarcoma cells in vitro. It was found that Ganoderma lucidum inhibits breast cancer cell growth and migration by suppressing Wnt/β-catenin signaling. It suppresses lung cancer through disruption of focal adhesions and induction of MDM2-mediated Slug degradation. Ganoderma lucidum inhibits breast cancer via downregulating the PI3K/AKT/mTOR pathway, [...]
Aging is determined by many factors besides the date of birth, but cellular senescence can be an important element of aging and age-related diseases. Several physiological and pathological conditions are subjects of aging research, including senescence, direct aging, photoaging, oxidative, mitochondrial, and inflammatory aging, among others. Schisandrin B and its analogue, schisandrin C, were shown to [...]