Why can reishi spore powder lower blood fats?

Inhibit cholesterol synthesis

To treat high blood cholesterol, we need to know what blood lipid is?

The main components of blood lipids are cholesterol and triglycerides. In order to reduce lipids, we need to reduce cholesterol and triglycerides in the body. Reishi spore powder can inhibit cholesterol synthesis.

How does reishi spore powder inhibit cholesterol synthesis?

First we need to know how cholesterol is synthesized. The liver synthesizes about half of the total cholesterol in the body.

How is it specifically synthesized?

Let’s take a look at it: acetate → 3-hydroxy-3-methylglutaric acid → mevalonate → … → cholesterol, which is the synthesis pathway of cholesterol in liver cells.

It includes more than 30 steps. We only need to know that “cholesterol” has been changed from “acetate”.

But how does reishi spore powder inhibit cholesterol synthesis. It’s ganoderma triterpenoids, one of the important components of reishi spore powder.

Ganoderma triterpenoids can directly inhibit the activity of HM-GCoA reductase. This reductase is a very important enzyme in the process of acetate to cholesterol. It controls the rate of acetate to cholesterol synthesis. The stronger its activity, the faster the cholesterol synthesis. Conversely, cholesterol synthesis becomes slower.

Ganoderma triterpenoids can inhibit the activity of HM-GCoA reductase, so it can naturally inhibit cholesterol synthesis in the liver.

Inhibit LDL oxidation

Besides lowering cholesterol,  how does reishi spore powder reduce low density lipoprotein?

The job of LDL is to carry cholesterol to all parts of the body. But when it is oxidized, he will do some bad things, and he will adhere cholesterol to the blood vessel wall. The blood vessel wall becomes thicker and thicker, less elasticity, arteriosclerosis finally.

So, if you want to reduce low density lipoprotein, there are two ways:

one is to directly reduce the amount of low density lipoprotein, the less the amount of LDL, the less the amount of cholesterol transportation.

Secondly, it is to prevent low density lipoprotein from being oxidized, and if it is not oxidized, it will not easily stick to the blood vessel wall.

Reishi spore powder can directly reduce low density lipoprotein.

In addition, the polysaccharides in reishi spore powder can inhibit the oxidation of low-density lipoprotein, to prevent arteriosclerosis.

New question: How ganoderma lucidum polysaccharides prevent LDL from being oxidized?

It is very simple, ganoderma lucidum polysaccharides can enhance the activities of “high glutathione peroxidase” and “superoxide dismutase”.

They are two important antioxidant substances in the human body. They can clear free radicals or human wastes. The stronger the activity of these two, the more powerful the body’s antioxidant capacity, and the less likely LDL will be oxidized.