1. Patients with cold and fever

When the human body has a cold and fever, the body’s healthy Qi (resistance) is in a fierce battle with external pathogenic factors (such as viruses, bacteria, etc.). Astragaloside IV has a certain tonic effect. Taking it in this situation may cause pathogenic factors to linger in the body. For example, if a person is infected with the influenza virus and has a fever, taking astragaloside IV at this time may prolong the duration of the fever symptoms or complicate the condition, which is not conducive to the body’s recovery.

  1. People with yin deficiency and yang hyperactivity

Yin deficiency and yang hyperactivity is a syndrome in traditional Chinese medicine, mainly manifested as tidal fever, night sweats, feverish sensation in the palms, soles, and chest, dizziness, and tinnitus. Astragaloside IV is a warm-natured medicine. Taking it by people in this category may aggravate the symptoms of yang heat in the body. It’s just like adding firewood to a stove that is already burning vigorously, which will make the heat symptoms in the body more obvious. For example, a patient with yin deficiency and yang hyperactivity, who already often feels irritable and hot and dry, may experience aggravated dry mouth and further aggravated insomnia after taking astragaloside IV.

  1. People with excessive damp-heat in the body

Common symptoms of people with excessive dampness and heat in the body include a bitter taste in the mouth, bad breath, sticky and uncomfortable stools, and a yellow and greasy tongue coating. The tonic nature of astragaloside IV may fuel the dampness and heat pathogenic factors in the body. For example, for a person with damp-heat diarrhea (frequent stools, sticky texture, and foul smell), taking astragaloside IV may aggravate the diarrhea symptoms because it will make the dampness and heat in the body even more difficult to be discharged.

  1. Pregnant women and breastfeeding women (use with caution)

For pregnant women, the safety of astragaloside IV has not been fully clarified. During pregnancy, the body is in a special physiological state, and drugs may affect the development of the fetus through the placenta. Although astragaloside IV has some benefits, if used improperly, it may bring potential risks. If breastfeeding women take astragaloside IV, the drug components may be passed on to the baby through breast milk. Since the baby’s body organs are not yet fully developed, they may be relatively sensitive to drug components. Therefore, these two groups of people generally need to use it with caution and it is best to decide whether to take it under the guidance of a doctor.