General Details
Product name: Gardenia jasminoides fruit extract.
Plant latin name: Gardenia jasminoides.
Product specifications: Genipin 98% HPLC.
Appearance: White powder or crystal.
- Long-term exposure to air will slowly turn yellow.
- It has an anticholinergic inhibitory effect on gastric function and is the substance with the strongest mutagenic activity among the iridoid glycosides discovered so far. 3. Soluble in ethanol, acetone, chloroform, ether, etc.; slightly soluble in water.
Genipin is the product of geniposide hydrolyzed by beta-glucosidase and is an excellent natural bio-crosslinking agent. The preparation method of genipin mainly includes extracting geniposide from Gardenia jasminoides and then preparing it through enzymatic hydrolysis, extraction, concentration, and recrystallization.
Health benefits
Anti-inflammatory effect
Genipin can inhibit the release of inflammatory mediators and regulate the inflammatory response process, thereby alleviating inflammatory symptoms and promoting tissue repair. This property makes genipin show good efficacy in the treatment of immune system diseases such as rheumatoid arthritis and systemic lupus erythematosus.
Antibacterial effect
Genipin-1-β-D-gentiobioside, as an antibiotic, can effectively inhibit the growth and reproduction of bacteria. It enters bacterial cells by penetrating the bacterial wall and interferes with the protein synthesis process, thereby inhibiting the proliferation of bacteria. This property makes genipin important in the treatment of infectious diseases such as respiratory tract infections, urinary tract infections, and skin infections.
Anti-tumor effect
Genipin also shows potential in anti-tumor. It can have a certain therapeutic effect on malignant tumors such as leukemia and lymphoma by inhibiting the proliferation of tumor cells and inducing their apoptosis.
Liver disease treatment
Genipin can be used to treat liver diseases, lower blood pressure, relieve constipation, and relieve symptoms of type II diabetes.
Applications
Biomedical materials
Genipin cross-linked biomaterials such as artificial bones and wound dressing materials not only have good biocompatibility and degradability but can also stably exist in the body and play a therapeutic role. These materials have broad application prospects in orthopedics, surgery, and other fields.
High-end gardenia blue and gardenia red pigment products can be prepared. They are a safe, non-toxic, and side-effect-free natural pigment, widely used in the coloring of food, medicine, and cosmetics.
Tissue engineering
Genipin-fixed biological tissues such as bovine pericardial stents can provide a good microenvironment after implantation in the body, promoting tissue regeneration and repair. This feature makes Genipin have important application value in the field of tissue engineering.
At the same time, it is an excellent fingerprint collection reagent and a good helper for the police to solve cases.