Product name: Mulberry Leaf Extract
Plant latin name: Morus alba L.
Product specifications: 1-Deoxynojirimycin 1%, 2%, 10%, 20% HPLC
Appearance: Pale brown powder
CAS No.: 19130-96-2
Molecular formula: C6H13NO4
Molecular weight: 163.17
Lowering blood lipid
Research shows mulberry leaf extract helps lowering blood lipids due to its active substances: phytosterols, flavonoids and isoflavones. Studies have reported that phytosterols and flavonoids can inhibit intestinal absorption of cholesterol, flavonoids can also reduce blood viscosity, strengthen the capillaries, improve the heart. Mulberry leaves can help urinating while draining away the excess water in cells. Therefore, mulberry leaves can improve hyperlipidemia to prevent myocardial infarction and stroke.
Lowering blood sugar
The structure of 1-Deoxynojirimycin is similar to α-1,4-glucagon, which can compete competitively with glucose in the body and thus can be used as a drug for people with diabetes. Research found that 1-Deoxynojirimycin can significantly improve blood glucose level and glucose tolerance in diabetic patients, which is highly sensitive for insulin.
Studies showed that 1-Deoxynojirimycin can significantly inhibit the invasion, metastasis and cell adhesion of B16F10 cells to the body, inhibiting the activity of MMP-2 only at 50μg / ml dose, inhibiting MMP-9 at 50μg / ml dose at 20%; the inhibition rate of MMP-2 and MMP-9 mRNA and the inhibition rates of both expressions are respectively 60% and 28%; Based on the above data analysis, 1-Deoxynojirimycin can be used to inhibit cancer metastasis.
1-Deoxynojirimycin can glycosylate the gpl20 protein on the surface of HIV virus, inhibiting the modification of glucose during protein translation, and block the binding of receptor to HIV Glycoprotein gpl20, so that HIV virus can’t enter into the recipients’cells.