Product name: Honeysuckle Extract
Plant latin name: Lonicera japonica Thunb.
Product specifications: Chlorogenic acid 5-25% UV
Appearance: Brown powder
CAS No.: 327-97-9
Molecular formula: C16H18O9
Molecular weight: 354.31
Antibacterial and anti-virus: Studies suggested that honeysuckle has obvious antiviral effect, the active ingredient is chlorogenic acid, the antiviral effect of honeysuckle is directly on the virus mostly by chlorogenic acid, which has certain inhibitory effect on DNA and RNA viruses. Honeysuckle extract can significantly prolong the survival of mice infected with influenza A virus, significantly reduce the number of deaths in mice infected with influenza A virus, has a significant protective effect on influenza A virus-infected mice. At the same time honeysuckle extract can significantly reduce the lung index value of influenza A virus-infected mice, alleviating the pulmonary lesions of influenza A virus-infected mice.
Honeysuckle extract has a strong pathogenic microorganism’s resistance, mainly against Staphylococcus aureus, Staphylococcus aureus, hemolytic streptococcus, Klebsiella pneumoniae, meningococcus, Salmonella typhi, paratyphoid bacillus, Escherichia coli, Shigella Proteus, Bordetella pertussis, Pseudomonas aeruginosa, Mycobacterium tuberculosis, cholera bacteria and other Gram-positive bacteria and Gram-negative bacteria. The active ingredients of antibacterial activity include chlorogenic acid, chlorogenic acid, gingko acid, caffeic acid, luteolin, luteolin-7-glucoside and volatile oil.
The experimental results also show that the honeysuckle extract has a strong inhibitory effect on Staphylococcus aureus, Bacillus pumilus, Bacillus subtilis and clinical isolates of pneumococcus, Staphylococcus epidermidis, Staphylococcus aureus, Escherichia coli, Streptococcus B, Staphylococcus, Pseudomonas sp.
Antioxidation: Chlorogenic acid is an effective phenolic antioxidant with stronger antioxidant level than caffeic acid, parabens, ferulic acid, syringic acid, butylated hydroxyanisole (BHA) and tocopherol. Chlorogenic acid contains a certain amount of R-OH group and can form hydrogen radical which eliminates the free radicals such as hydroxyl radical and superoxide anion, protecting tissues from oxidative damage.
Anti-aging: Chlorogenic acid and its derivatives have stronger free radical scavenging effect than ascorbic acid, caffeic acid and vitamin E, which can effectively scavenge DPPH radical, hydroxyl radical and superoxide anion free radicals, but also inhibit the oxidation of low-density lipoprotein. Chlorogenic acid plays an important role in effectively eliminating free radicals in the body, maintaining the normal structure and function of cells in the body, and preventing and delaying the occurrence of tumor mutation and aging.
Cardiovascular protection: As a free radical scavenger and antioxidant, a lot of experiments have proved that chlorogenic acid has strong cardiovascular system protection. Isochlorogenic acid B has a strong promotion of prostacyclin (PGI2) release and anti-platelet aggregation; iso-chlorogenic acid C also promotes the release of PGI2. In addition, iso-chlorogenic acid B has a strong inhibitory effect on thrombospondin biosynthesis and hydroperoxide-uninduced endothelin damage.
Other Benefits: Since chlorogenic acid has a specific inhibitory effect on HAase and Gl-6-Pase, chlorogenic acid can cure wounds, moisturize the skin and lubricate joints, prevent inflammation and balance blood glucose. Chlorogenic acid also have a strong inhibitory and killing effect on a variety of diseases and viruses. Chlorogenic acid has the effects of antihypertensive, anti-bacterial, anti-virus, anti-inflammatory, increasing white blood cells, prevents diabetes, significantly increasing gastrointestinal peristalsis and promoting gastric secretion and other pharmacological effects on acute pharyngitis. Studies have shown that supplementing chlorogenic acid can significantly stimulate the secretion of bile to keep liver working effectively; chlorogenic acid is also effective in inhibiting hemolysis of rat erythrocytes caused by H2O2.